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/ α-GalNAc-PEG5000-Thiol / α-D-GalNAc-PEG5000-Thiol
/ β-D-LacNAc-Butyl-Carboxylic Acid / β-LacNAc-C4-COOH
/ α-D-Man-Butyl-Carboxylic Acid / α-Man-Bu-CO2H
MUC5AC is a synthetic 16 amino acid glycopeptide fragment and tandem repeat sequence of MUC5AC (Gly2449-Pro2464) where O-glycosylation (GalNAc) is at amino acid Thr3 and Thr13(Thr2451 and Thr2461 in protein)
62 / An Fmoc-protected L-serine building block carrying an α-D-mannose residue
PE634005: α-Man-PEG3-Azide (Peracetate) label-new / α-GalNAc-PEG5000-Thiol / α-D-GalNAc-PEG5000-ThiolC20H31N3O12 505. 47 A peracetylated D mannose ligand equipped with an azide handle through a hydrophilic PEG3 spacer. The terminal azide couples to alkynes via copper catalyzed azide alkyne cycloaddition (CuAAC) or to DBCO and related strained alkynes via copper free click chemistry, forming stable 1,2,3 triazole linkages. The sugar hydroxyls are acetate protected to increase lipophilicity for cell membrane permeability. This compound provides an D
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